Post-Doctoral Position - Mucosal Immunology

Company: Zoetis, Inc
Location: Kalamazoo
Posted on: March 19, 2023

Job Description:

Company: ZoetisTitle: Post-Doctoral Position - Mucosal ImmunologyLocation: Kalamazoo, Michigan, USAThe Zoetis DST Mechanistic Biology Kalamazoo group is seeking an innovative and highly motivated post -doctoral immunologist with expertise in mucosal immunology related to infectious and non-infectious diseases to contribute towards discovery and development of novel therapies for veterinary species. The Mechanistic Biology group within Discovery Sciences &Technologies works across various therapeutic areas and is geared towards understanding the immunological basis of inflammation, infectious/non-infectious disease, and host-pathogen interactions in order to identify, evaluate, and progress therapeutic targets and substrates for companion animals and livestock.Responsibilities:*Develop/optimize and implement novel in vitro and ex vivo cell culture models to assess immunological mechanisms of infectious diseases/host-pathogen interactions & therapeutic targets relevant to mucosal immunity*Characterize immunological responses in in vitro, ex vivo, and in vivo model systems using multiple technical approaches to elucidate interactions between immune cells and non-immune cells in mucosal sites as they relate to host-pathogen interactions, immunopathology, and immunomodulation*Perform routine and complex, specialized, laboratory procedures including cell culture and various immunoassays for investigators*Work closely with the Mechanistic Biology, Genetics/Bioinformatics, Livestock Research groups to provide expert advice/service in mucosal immunology, experimental design development/execution and application of immune assays towards identification and validation of therapeutic targetsBasic Qualifications:Suitable candidate will have a PhD in immunology or related biomedical/biology area with a focus in mucosal immunology, innate immunology, infectious disease, and inflammation. Has extensive experience developing in vitro and ex vivo cell culture systems to address immunobiological questions in mucosal immunity and infectious disease. Has enthusiasm to learn new immunoassays/techniques and investigate variety of different disease areas. Has ability to work independently in research projects within area of specialization. Candidate must also be a creative/independent thinker and with a track record of research in innate/mucosal immunology and peer reviewed publications in relevant areas.Desired Skill sets:*In-depth knowledge of mucosal immunology and strong experience in related in vitro and ex vivo techniques with emphasis in innate immunity and infectious disease, preferably with background in veterinary immunology
*Strong practical expertise in developing and implementing in vitro mono- and co-culture culture techniques to investigate immunological mechanisms of host-pathogen interactions (preferably bacterial) and inflammation relevant to mucosal immunity; strong understanding of translation of in vitro/ex vivo model systems to in vivo models*Strong practical expertise in developing, implementing, and analyzing data from a range of immunological techniques for ex vivo and in vitro models including cell culture (primary & immortalized, immune & non-immune), ELISA (or preferably multiplex assays e.g. MesoScale Discovery U-Plex assays, Luminex), immunohistochemistry, and flow cytometry (experience with FlowJo analysis preferred)*Experience with bacterial or viral in vitro culture techniques for use in in vitro infection models*Experience with techniques in RNA/protein isolation and qPCR and/or RNA-Sequencing from tissue/cell culture*Experience with live cell fluorescent imaging techniques (Incucyte, confocal microscopy, etc.)*Experience/familiarity with 3-D cell culture systems to elucidate mucosal immunological mechanismsZoetis is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status or any other protected classification. Zoetis also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must possess or obtain authorization to work in the US for Zoetis. Zoetis retains sole and exclusive discretion to pursue sponsorship for the acquisition or maintenance of nonimmigrant status and employment eligibility, considering factors such as availability of qualified US workers. Individuals requiring sponsorship must disclose this fact.Full timeRegularColleagueAny unsolicited resumes sent to Zoetis from a third party, such as an Agency recruiter, including unsolicited resumes sent to a Zoetis mailing address, fax machine or email address, directly to Zoetis employees, or to Zoetis resume database will be considered Zoetis property. Zoetis will NOT pay a fee for any placement resulting from the receipt of an unsolicited resume.Zoetis will consider any candidate for whom an Agency has submitted an unsolicited resume to have been referred by the Agency free of any charges or fees. This includes any Agency that is an approved/engaged vendor but does not have the appropriate approvals to be engaged on a search.Zoetis is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status or any other protected classification. Disabled individuals are given an equal opportunity to use our online application system. We offer reasonable accommodations as an alternative if requested by an individual with a disability. Please contact Zoetis Colleague Services at zoetiscolleagueservices@zoetis.com to request an accommodation. Zoetis also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must possess or obtain authorization to work in the US for Zoetis. Zoetis retains sole and exclusive discretion to pursue sponsorship for the acquisition or maintenance of nonimmigrant status and employment eligibility, considering factors such as availability of qualified US workers. Individuals requiring sponsorship must disclose this fact. Please note that Zoetis seeks information related to job applications from candidates for jobs in the U.S. solely via the following: (1) our company website at www.Zoetis.com/careers site, or (2) via email to/from addresses using only the Zoetis domain of "@zoetis.com". In addition, Zoetis does not use Google Hangout for any recruitment related activities. Any solicitation or request for information related to job applications with Zoetis via any other means and/or utilizing email addresses with any other domain should be disregarded. In addition, Zoetis will never ask candidates to make any type of personal financial investment related to gaining employment with Zoetis.

Keywords: Zoetis, Inc, Kalamazoo , Post-Doctoral Position - Mucosal Immunology, Healthcare , Kalamazoo, Michigan