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Scientist / Senior Scientist

Company: Zoetis
Location: Kalamazoo
Posted on: June 7, 2021

Job Description:

The Biopharmaceutical Development group in Zoetis Veterinary Medicine Research and Development is seeking a talented bioprocess scientist or engineer to join our efforts in the design and development of bioprocesses for manufacture of novel protein therapeutics and monoclonal antibodies intended for veterinary medicine applications. The successful candidate should have hands-on experience in the development and optimization of mammalian bioreactor processes for efficient production of biotherapeutic proteins. Experience across multiple process scales is required including; shaker flask cultures, laboratory reactors, and pilot scale reactors. Experience with single-use bioreactor systems, perfusion culture mode systems, and the ability to conduct experiments within a factorial design (DoE) will be highly regarded. The successful candidate will work with minimal supervision in carrying out their assigned tasks in experimental development of bioreactor processes for GMP manufacture. This job requires an independent thinker with a demonstrated ability to innovate at the bench and collaborate effectively with other team members. Work will be performed in an independent manner with periodic review against agreed objectives. The successful candidate will have a track record in the application of both theoretical and practical knowledge of bioreactor systems to find working solutions for the numerous scientific challenges encountered in this discipline. Having a team-oriented approach and excellent communication skills are essential.

Position Responsibilities:

Design and conduct bioreactor experiments to identify and validate critical parameters that affect fermentation performance across multiple scales. The parameters to be investigated include reactor configuration, medium composition, and fed batch strategies.

Systematically optimize the parameters that affect bioreactor performance through the application of statistical models for experimental design and analysis.

Partner with scientists working in cell line development to conduct screening experiments with purpose to identify high-performing cell lines.

Work in partnership with colleagues in pilot and manufacturing scale operations to devise scale-up strategies for bioreactor processes.

Drive innovation and continuous improvement by conducting laboratory experiments to evaluate new bioprocess technologies.

Document experimental findings through periodic authorship of progress reports to be included in dossiers for product registration and technology transfer.

Serve as upstream development lead on project teams which includes willing sharing of research findings with team members, peers, and management.

Maintain electronic laboratory notebooks and records in accord with scientific protocol and applicable Standard Operating Procedures.

Education and Experience:

A relevant degree in science or engineering. BS with 5 years of experience or MS/PhD with 2 years

A minimum of 2 years' experience in the development of bioreactor processes.

Both theoretical and practical knowledge of the parameters the affect bioreactor design and performance.

Experience in sterile technique for mammalian cell culture.

Full time



Zoetis is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status or any other protected classification. Disabled individuals are given an equal opportunity to use our online application system. We offer reasonable accommodations as an alternative if requested by an individual with a disability. Please contact Zoetis Colleague Services at zoetiscolleagueservices@zoetis.com to request an accommodation. Zoetis also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must possess or obtain authorization to work in the US for Zoetis. Zoetis retains sole and exclusive discretion to pursue sponsorship for the acquisition or maintenance of nonimmigrant status and employment eligibility, considering factors such as availability of qualified US workers. Individuals requiring sponsorship must disclose this fact. Please note that Zoetis seeks information related to job applications from candidates for jobs in the U.S. solely via the following: (1) our company website at www.Zoetis.com/careers site, or (2) via email to/from addresses using only the Zoetis domain of "@zoetis.com". In addition, Zoetis does not use Google Hangout for any recruitment related activities. Any solicitation or request for information related to job applications with Zoetis via any other means and/or utilizing email addresses with any other domain should be disregarded. In addition, Zoetis will never ask candidates to make any type of personal financial investment related to gaining employment with Zoetis.

Keywords: Zoetis, Kalamazoo , Scientist / Senior Scientist, Other , Kalamazoo, Michigan

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