Formulation Scientist

Company: Zoetis, Inc
Location: Kalamazoo
Posted on: January 24, 2023

Job Description:

FORMULATION SCIENTISTWe are seeking an experienced formulation scientist to develop new veterinary drug products and reformulate existing products. The formulation scientist will be responsible for: 1) screening new chemical entities, 2) conducting formulation screening and optimization studies, 3) characterizing drug products, and 4) developing manufacturable formulation processes. Dosage forms may include sterile injectables (liquid and lyophilized), oral liquids, topicals/transdermals, and others for a variety of animal species. The scientist will work with interdisciplinary teams such as chemistry, clinical, analytical, regulatory, and others to guide projects from early discovery through product launch. The scientist may be expected to lead formulation teams, and work with junior and senior formulation scientists to advance formulations through to approval. RESPONSIBILITIES

• Pre-formulation development, including screening new chemical entities and formulations to solve solubility, stability, and absorption challenges.
• Support discovery team with enabling formulations, and generation of experimental supplies for early-stage studies.
• Author study protocols, development reports, and regulatory documents for filing and commercial launch.
• Formulation design, characterization, development, and process scale-up including transfer to global manufacturing sites.
• Research and development of drug delivery systems internally and/or through external partners.
  EDUCATION AND EXPERIENCE
  • BS (> 10 years' experience), MS (> 5 years' experience) or PhD (> 5 years' experience) in Pharmaceutics, Chemistry, Chemical Engineering, or related field.
  • Experience in conducting pre-formulation and formulation development studies.
  • Knowledge in Biopharmaceutics, Pharmacokinetics, Chemistry, and vehicle/excipient selection.
  • Experience working in matrix-like teams and collaborating with diverse scientists, including external partners.
  • Extensive knowledge of API properties, drug degradation pathways, solubilization, and stabilization techniques.
  • Experience in authoring supporting documentation for regulatory filings.
  • Effective and demonstrated communication and leadership skills.
  • Solid understanding of statistics and graphing software.
    OTHER DESIRABLE ATTRIBUTES
    • Solid understanding of Quality by Design, and Design of Experiment approaches and techniques.
    • Familiarity with GMP, VICH, Pharmacopeial, Technical and Regulatory requirements in relation to animal health product development and manufacturing.
    • Familiarity with manufacturing process development, scale-up, technology transfer to pilot/commercial scale.
    • Understanding of packaging considerations for commercial products and primary pack screening and selection activities
    • Familiarity of the Animal Health industry with experience of working with Marketing/Commercial colleagues.
    • Use of statistical modeling for shelf-life determination and specification setting.
    • Experience with writing CMC technical sections and supporting post commercial changes.WHO WE AREZoetis is the leading animal health company. Our mission is to build on a six-decade history and singular focus on animal health to bring customers quality products, services and a commitment to their businesses. We are working every day to better understand and address the real-world challenges faced by those who raise and care for farm and companion animals in ways they find truly relevant.LOCATIONKalamazoo, Michigan, USAFull timeRegularColleagueZoetis is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status or any other protected classification. Disabled individuals are given an equal opportunity to use our online application system. We offer reasonable accommodations as an alternative if requested by an individual with a disability. Please contact Zoetis Colleague Services at zoetiscolleagueservices@zoetis.com to request an accommodation. Zoetis also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must possess or obtain authorization to work in the US for Zoetis. Zoetis retains sole and exclusive discretion to pursue sponsorship for the acquisition or maintenance of nonimmigrant status and employment eligibility, considering factors such as availability of qualified US workers. Individuals requiring sponsorship must disclose this fact. Please note that Zoetis seeks information related to job applications from candidates for jobs in the U.S. solely via the following: (1) our company website at www.Zoetis.com/careers site, or (2) via email to/from addresses using only the Zoetis domain of "@zoetis.com". In addition, Zoetis does not use Google Hangout for any recruitment related activities. Any solicitation or request for information related to job applications with Zoetis via any other means and/or utilizing email addresses with any other domain should be disregarded. In addition, Zoetis will never ask candidates to make any type of personal financial investment related to gaining employment with Zoetis.

Keywords: Zoetis, Inc, Kalamazoo , Formulation Scientist, Other , Kalamazoo, Michigan