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Postdoctoral Scientist - Protein Therapeutics

Company: Zoetis, Inc
Location: Kalamazoo
Posted on: January 25, 2023

Job Description:

The Protein Therapeutics group within Global Therapeutics Research at Zoetis has the mission and responsibility for identifying and delivering novel large and small molecule therapeutics for a diverse array of indications. We are seeking a talented and experienced postdoctoral scientist to join our efforts in the exploration of novel screening and expression technologies. The ideal candidate will have experience with phage and/or yeast display and the generation and characterization of peptide/protein libraries. Working experience with both prokaryotic and eukaryotic expression systems and knowledge of current gene editing platforms is highly desirable. Day-to-day activities will include identification and evaluation of fit-for-purpose approaches for the generation and expression of reagent proteins to address individual VMRD project analytical requests. This position will also take a leadership role in discussions with external partners and oversight of technology collaborations.The successful candidate will have a PhD or equivalent in scientific discipline with emphasis in protein engineering, cell biology, molecular biology or related field. Excellent communication, organizational and interpersonal skills are essential. POSITION RESPONSIBILITIES:

  • Design and/or generation of display libraries in multiple formats (phage, yeast, mammalian)
  • Identification and evaluation of novel platforms for the expression of recombinant proteins
  • Engage external technology partners and internal cross-functional teams, assisting with the design and providing oversight of collaborative efforts
  • Protein purification (mAbs, therapeutic proteins, reagent proteins, peptides) by affinity or native methods
  • Analytical characterization of proteins by SDS-PAGE, CGE, Western Blot, ELISA and analytical SEC
  • Prepare precise technical report summaries, protocols, analysis and maintain appropriate documentation
  • Maintain high scientific rigor and attention to detail in testing hypotheses and analyzing dataEDUCATION AND EXPERIENCE:
    • Educational background: PhD or equivalent in scientific discipline with emphasis in protein engineering, cell biology, molecular biology or related field
    • Training and demonstrated proficiency in cell biology and aseptic cell culture with a wide variety of cell types
    • Working knowledge in molecular biology, cloning and protein analysis techniques (SDS-PAGE, Western Blot, ELISA)
    • Recombinant protein expression experience in prokaryotic (E. coli) and eukaryotic (yeast, mammalian) systems
    • Experience in the generation and characterization of phage, yeast and/or mammalian display libraries
    • Experience with gene editing and cell manipulation for enhanced / engineered protein production
    • Ability to work independently and as part of a team, exhibiting self-motivation, adaptability, and a positive attitudeADDITIONAL INFORMATION:Work environment:The placement of this position will be primarily in Kalamazoo, MI. Occasional travel to other Zoetis sites may also be requested.The person filling this position will work predominantly in a laboratory setting. There may be exposure to animal pathogens and chemicals. Strict biosafety and biosecurity training will be completed prior to handling animal tissues and zoonotic organisms.Zoetis is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status or any other protected classification. Zoetis also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must possess or obtain authorization to work in the US for Zoetis. Zoetis retains sole and exclusive discretion to pursue sponsorship for the acquisition or maintenance of nonimmigrant status and employment eligibility, considering factors such as availability of qualified US workers. Individuals requiring sponsorship must disclose this fact.Full timeRegularColleagueAny unsolicited resumes sent to Zoetis from a third party, such as an Agency recruiter, including unsolicited resumes sent to a Zoetis mailing address, fax machine or email address, directly to Zoetis employees, or to Zoetis resume database will be considered Zoetis property. Zoetis will NOT pay a fee for any placement resulting from the receipt of an unsolicited resume.Zoetis will consider any candidate for whom an Agency has submitted an unsolicited resume to have been referred by the Agency free of any charges or fees. This includes any Agency that is an approved/engaged vendor but does not have the appropriate approvals to be engaged on a search.Zoetis is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status or any other protected classification. Disabled individuals are given an equal opportunity to use our online application system. We offer reasonable accommodations as an alternative if requested by an individual with a disability. Please contact Zoetis Colleague Services at zoetiscolleagueservices@zoetis.com to request an accommodation. Zoetis also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must possess or obtain authorization to work in the US for Zoetis. Zoetis retains sole and exclusive discretion to pursue sponsorship for the acquisition or maintenance of nonimmigrant status and employment eligibility, considering factors such as availability of qualified US workers. Individuals requiring sponsorship must disclose this fact. Please note that Zoetis seeks information related to job applications from candidates for jobs in the U.S. solely via the following: (1) our company website at www.Zoetis.com/careers site, or (2) via email to/from addresses using only the Zoetis domain of "@zoetis.com". In addition, Zoetis does not use Google Hangout for any recruitment related activities. Any solicitation or request for information related to job applications with Zoetis via any other means and/or utilizing email addresses with any other domain should be disregarded. In addition, Zoetis will never ask candidates to make any type of personal financial investment related to gaining employment with Zoetis.

Keywords: Zoetis, Inc, Kalamazoo , Postdoctoral Scientist - Protein Therapeutics, Other , Kalamazoo, Michigan

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